Phone : 732-342-6911      Email : sales@aswmedchem.com
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Services

ASW MedChem is proud of its record in synthesizing quality compounds at rapid speed. We are skilled at tackling complex synthetic routes with ease and on scales ranging from milligrams to kilograms. ASW Medchem has conducted a broad range of chemistry projects ranging from design and synthesis of biologically relevant heterocyclic systems through asymmetric synthesis, peptide chemistry, nucleoside chemistry and total synthesis of natural products.

overview

With an established reputation as one of the most reliable and high quality chemistry service providers in the world, ASW Medchem has the scientific expertise to support a vast range of discovery projects. Our years of experience in working with the world’s biggest pharmaceutical companies and most progressive biotech startups assist us in enhancing our partners’ discovery campaigns. With state-of-the art facilities and a team of dedicated scientists we are ready to support your efforts in these areas.

• Strong operational support for material sourcing and compound management
• Every chemist has access to SciFinder
• State-of-the-art equipment
• Responsive project management
• Broad therapeutic disease area expertise

ASW MedChem is proud of its record in synthesizing quality compounds at rapid speed. We are skilled at tackling complex synthetic routes with ease and on scales ranging from milligrams to kilograms. ASW Medchem has conducted a broad range of chemistry projects ranging from design and synthesis of biologically relevant heterocyclic systems through asymmetric synthesis, peptide chemistry, nucleoside chemistry and total synthesis of natural products.

  • Independent route design to complex target molecules and timely execution
  • Problem solving expertise and creativity
  • Responsive project management and seamless communication
  • Broad synthetic and therapeutic area expertise
  • Strong IP protection and strategic planning
  • Organic synthesis
  • Intermediate synthesis
  • Building block synthesis
  • Reference compound synthesis
  • Metabolite synthesis
  • Impurity synthesis
  • Bioorganic synthesis
  • Antibody drug conjugate synthesis
  • Process Discovery and Development
  • Reaction condition optimization
  • Route discovery, selection, and development
  • Impurity characterization and management
  • Reference standard preparation
  • Parallel chemistry
  • Hit expansion
  • SAR exploration
  • Focused libraries
  • Scale-up to non-GMP drug substance
  • Synthesis of up to 5 kg of final product

Manufacturing Capabilities

Milligrams to Kilograms
Asymmetric Synthesis
Low Temperature, High Temperature, High Pressure Reactions
Various Reactions
60,000 ft2 R&D Research Facilities
50-60 Synthetic Chemists

Analytical Capabilities

NMR (1H, 13C, 19F, 31P, 2D COSY and NOESY)
HPLC, LCMS, HRMS
GC, GCMS
Optical Rotation
IR, Elementary Analysis
X-Ray Structure Analysis

Major Analytical Instrument List

Bruker AVANCE 300 MHz NMR and 400 MHz NMR
Waters Micro-Q-Top MicroTM HRMS; Agilent 6540 HRMS
Agilent 1100 LCMS; Agilent 1200 LCMS
Thermo Trace GC DSQ II GCMS; Thermo Trace-ISQ GCMS
Bruker 220 IR; Elementar Vario EL III; Perkin Elmer PE 341 Polarimeter
Agilent 1200 HPLC; Waters 2489 HPLC; Agilent 7890A GC
Oxford/Varian Gemini E XRD